Subject: AUC dose experienced by the subject pharm. A still further advantage of the compositions of the present invention is the linearity of the "AUC dose experienced by the subject " in comparison with the administered dose of buprenorphine.The depot composition of claim 19 or claim 20 which, upon administration to said subject provides linearity (proportionality) of the "AUC dose" in comparison with the administered dose of buprenorphine AUC-площадь под фарм кривой. Как понять AUC dose experienced by the subject Заранее спасибо! |
похоже, здесь речь идет о биодоступности а то бывает влили килограмм, а биодоступность типа всего 20% |
Еще контекст: A still further advantage of the compositions of the present invention is the linearity of the AUC dose experienced by the subject in comparison with the administered dose of buprenorphine. This may be seen from Figure 6 and allows the physician to control the experienced dose directly by control of the administered dose in a linear relationship. |
experienced dose и administered dose: в чем разница? |
dao2812, если на пальцах - доза, ощущаемая пациентом и введенная доза. |
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